Surgery is the main treatment of diabetic foot just like many other chronic wounds. However, sometimes it is not efficient enough by itself, and has to be supported by adjuvant therapies. Some of these adjuvant therapies may act by cellular, chemical, biological, or biochemical means. In this article however, we will evaluate the adjuvant therapies such as hyperbaric oxygen therapy, negative pressure wound therapy, ozone therapy, topical oxygen therapy, electrical stimulation, laser and similar light therapies which are basically the physically effecting treatment methods. Modern wound care dressings which also work physically will not be mentioned since they are discussed in another article in this issue.