In this review, the pathologies which magnetic resonance imaging (MRI) is highly sensitive for diagnosis in patients who are admitted with anterior knee pain and suspected patellofemoral joint disease were discussed. Patellofemoral joint anatomy, variations and pathologies, as well as MRI findings of degenerative diseases in acute and chronic phase were also explained. Detailed investigation is of utmost importance to allow early diagnosis and improve the quality of life of the patients with patellofemoral joint diseases.