TOTBİD Dergisi

TOTBİD Dergisi

2022, Cilt 21, Sayı, 5     (Sayfalar: 526-530)

Two-stage autologous chondrocyte implantation

Barış Kocaoğlu 1, Berhan Bayram 1, Alper Gamlı 1

1 Acıbadem Üniversitesi Tıp Fakültesi, Altunizade Hastanesi, Ortopedi ve Travmatoloji Kliniği, İstanbul

DOI: 10.5578/totbid.dergisi.2022.73
Görüntüleme: 494
İndirme : 349

Human articular cartilage is fed via the synovial fluid and the bone; therefore, its healing ability is limited. Palliative procedures such as debridement, microfracture, and drilling in cartilage lesions result in the formation of fibrous cartilage instead of hyaline cartilage. Autologous chondrocyte implantation and matrix-induced autologous chondrocyte implantation have been commonly applied as the treatment of cartilage lesions in recent years. The main objective of these techniques is to obtain a healing tissue closest to the hyaline cartilage in the means of regenerating tissue. In this paper, information about the indications, contraindications, application techniques, complications, postoperative rehabilitation, advantages and disadvantages of two-stage autologous chondrocyte implantation were reviewed.

Anahtar Kelimeler : regenerative medicine; autologous chondrocyte implantation; chondral injury