Osteomyelitis is the inflammation of the bone or bone marrow. The condition is characterised by systemic symptoms such as fever, fatigue and lack of appetite, as well as pain, erythema, swelling and local heat increase. C-reactive protein level, erythrocyte sedimentation rate and elevated white blood cell count are the most important laboratory findings. Long-term treatment with antibiotics results in bacteria that are resistant to antimicrobial therapy and extremely difficult to eradicate from the human body. The disease has several different clinical forms in addition to the typical presentations of osteomyelitis. Neglecting the disease or delay in the diagnosis may cause amputation.