A detailed history and physical examination is very important in the diagnosis of hand infections. Also radiological studies such as X-rays, magnetic resonance imaging and ultrasound and laboratory studies such as complete blood count, C-reactive protein and sedimentation rate are used in the diagnosis. Gram stain, culture and antibiotic sensitivity determinations are mandatory in the diagnosis and treatment. Generally, the methods used in the treatment include resting the affected extremity, appropriate antibiotic treatment and surgical drainage-debridment. While Staphylococcus aureus is the most commonly isolated pathogen, many other bacteria and fungi can be the causative agent in hand infections. In many cases more than one microorganism are isolated. The most common hand infection is paronychia (infection of the soft tissue around the finger nail). Also felon (infection of the pulp), pyogenic tenosynovitis, infections seen in the subfascial and deep fascial spaces of the hand, web space infections, infections of the radial and ulnar bursae, septic arthritis and osteomyelitis are the other commonly seen infections of the hand.