Diabetic foot is increasing its frequency while decreasing quality of life, since it is an important cause of morbidity and mortality in the world. Good glycemic control, regular foot examination, appropriate shoe selection and patient education can prevent the disease before it can have serious impacts. Unavoidable situations might cause foot infection, foot ulceration, soft tissue and bone destruction. For treating such cases multidisciplinary approach is important. However, priority should be given to conservative treatment options. In advanced cases, surgical approaches ranging from simple debridement to major amputation are frequently used. Amputations are not as harmless as it is thought and can increase mortality. Treatment choices should be made for each patient with appropriate care.