Lateral patellofemoral compression syndrome (LPCS) is a lower extremity malalignment, mainly presenting with anterior knee pain. Excessive lateral retinacular tension results in lateral patellar tilt, however patella is still centered in the femoral sulcus. Patellofemoral disorders with anterior knee pain have a wide spectrum. Lateral patellofemoral compression syndrome should be differentiated from anterior knee pain with normal patellofemoral tracking and patellofemoral instability using a detailed medical history, physical examination and appropriate imaging techniques. The disease is mainly managed using conservative treatment modalities. Arthroscopic lateral release may result in successful outcomes in selected patients who are refractory to the conservative treatment. In this article, currents approaches for the management of LPCS were reviewed.