TOTBİD Dergisi

TOTBİD Dergisi

2019, Cilt 18, Sayı, 6     (Sayfalar: 578-584)

Lung cancer metastases to bone

Hüseyin Sina Coşkun 1, Nevzat Dabak 2

1 T. C. Sağlık Bilimleri Üniversitesi, Samsun Eğitim ve Araştırma Hastanesi, Samsun
2 Samsun Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Ortopedi ve Travmatoloji Anabilim Dalı, Samsun

DOI: 10.14292/totbid.dergisi.2019.75
Görüntüleme: 516
İndirme : 3802

Lung cancer is one of the most important causes of cancerrelated mortality nowadays. Despite all modern diagnostic methods available today, early detection of the lung cancer is not always possible in most patients. One of the most important complications of lung cancer is metastasis to bone tissue. Lung cancer ranks third among the most common cancers that metastasize to bone, and approximately 40% of lung cancer patients have bone metastases during the course of the disease, and survival is significantly reduced in lung cancers with bone metastases. Quality of life and mobilization of patients are significantly decreased, as load bearing sites are usually affected in patients with bone metastases. The treatment methods in the lung tissue metastases are similar to the treatment of metastatic bone cancer caused by other foci. In the light of this information, the primary aim of treatment is to reduce the pain caused by metastases, to treat fractures and other complications, or to prevent these complications and improve the quality of life of the patient as much as possible. General treatment methods for metastatic bone disease include palliative treatments with pain-controlling drugs and therapies, medical treatments combined with radiotherapy, bonespecific treatments such as bisphosphonates and radioactive isotopes, and surgical interventions. In this review article, following the overview of lung cancer and its subtypes, we will review the pathophysiology and treatment of the bone metastasis.

Anahtar Kelimeler : lung carcinoma; bone metastasis; metastases