Solid organ metastases most commonly occur in the lungs, then in the liver, and third in the bone. A patient with bone metastases should not be considered as a person who has come to the end of his life. Patients can survive for many years, especially due to recent developments in both chemotherapy and radiotherapy. Healing may occur in patients with solitary bone metastases as in patients with primary bone tumors. The aim of radiotherapy in patients with bone metastasis is to improve the quality of life, to maintain skeletal functions, and to reduce and if possible to stop the use of painkillers. To accomplish these, the main objectives are to prevent or eliminate tumor progression, pathological fracture formation, and spinal cord compression. The importance of multidisciplinary approach in the treatment of patients with metastatic bone lesion should not be forgotten, and no surgery should be performed without such a treatment plan. Radiotherapy, as a treatment modality in patients who have metastatic lesions of the long bone, should be planned according to the Mirels` scoring system whilst in patients with vertebral metastasis according to the NOMS framework. In addition, radiotherapy in patients with metastases, aside from preventing fracture union, destroys tumor cells and therefore provides a suitable environment for union.