TOTBİD Dergisi

TOTBİD Dergisi

2014, Cilt 13, Sayı, 3     (Sayfalar: 240-246)

Chondrosarcomas

Yener Sağlık 1

1 Ankara Üniversitesi Tıp Fakültesi, İbn-i Sina Hastanesi, Ortopedi ve Travmatoloji Anabilim Dalı, Ankara

DOI: 10.14292/totbid.dergisi.2014.26
Görüntüleme: 55
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İndirme : 64

Chondrosarcoma is a malignant primary bone tumor, arising from the cartilage-producing chondrocytes, ranging from slow-growing, non-metastasizing lesions to very aggressive and metastasizing lesions. Clinical behavior is generally consistent with the histological properties of the lesion. Histologically, chondrosarcomas are divided into three subgroups (Grade 1, 2, and 3) with respect to properties such as cellular atypia and cellularity. In addition, subtypes have been identified such as secondary, myxoid, dedifferentiated, clear cell, mesenchymal, periosteal chondrosarcoma. The most prominent feature of cartilage lesions is the presence of calcifications and opacities on radiographs. Typically, there are spotty opacities within an area of lucency. X-rays, computerized tomography (CT) and magnetic resonance (MR) imaging are the most commonly used tools for diagnosis. The cortex is slightly expanded and thinned and there is endosteal scalloping in the affected area in a long bone. MR and CT are useful in assessing the condition of soft tissues and medullary cavity. Primary treatment for chondrosarcomas is wide surgical excision, whereas chemotherapy and radiotherapy can be used for conservative treatment in metastatic patients.

Anahtar Kelimeler : chondrosarcoma; secondary chondrosarcoma; periosteal chondrosarcoma; myxoid chondrosarcoma; mesenchymal chondrosarcoma; dedifferentiated chondrosarcoma; clear cell chondrosarcoma