Entrapment neuropathy is the result of compression of the peripheral nerve at certain points along the anatomical course caused by various reasons, and characterized by the motor, sensory and autonomic deficits. Entrapment neuropathies are more prevalent in the upper extremities; the most common of these are the carpal tunnel syndrome which is the compression of median nerve of the wrist, and the cubital tunnel syndrome which is the compression of ulnar nerve at the elbow. The treatment of nerve entrapment in the acute phase varies according to factors such as the location, cause, size and duration of the compression. In the acute phase of entrapment neuropathy and in cases with mild symptoms, the preferred treatment method is conservative. During this period, the purpose of conservative treatment is to reduce inflammation by positioning the extremity in suitable rest position, often by the help of splints, keep in control pain and edema, and maintain nerve excursion. In cases which do not respond to conservative treatment, surgical decompression is performed. Conservative treatment is planned after surgical treatment, especially for the treatment of motor and sensory deficits of the patients.