Risky babies are infants who are followed up in neonatal intensive care units with diagnoses such as prematurity, intrauterine growth retardation, congenital infection, neonatal encephalopathy, neonatal convulsions, and respiratory distress. Risky infants are at risk for developmental delay, sensorineural problems (vision, hearing and speech disorders), language stress, behavioral problems and psychosocial problems. Cerebral palsy (CP) can be seen in about 5–10% of very low birth weight infants, and cognitive or behavior problems in 25%. In twins, the risk of prematurity and intrauterine growth retardation and the CP risk increases 7 times compared to single infants. Of the patients with perinatal asphyxia, cerebral palsy is seen in 30%, and cognitive and developmental problems is seen in 45%. Before and after discharge the follow-up of risky babies should be done by a team from different disciplines including neonatologist, general pediatrician, pediatric neurologist, audiologist, child development specialist, eye specialist, physiotherapist, respiratory therapist, speech and language therapist, and dietitian. The aim of risky baby follow-up is to detect the problems of these babies in early period, and to improve the prognosis with early interventions; and by so, to increase the quality of life of the baby and the family.