Patients may develop many different complications after orthopedic surgical interventions. Mobilization is a critical component in supporting recovery and rehabilitation in the postoperative period. Therefore, ensuring the mobilization of patients in the postoperative period, preventing complications caused by immobility, maintaining homeostatic balance and accelerating recovery are among the important goals of nursing care. Although mobilization plays such an important role in the recovery process of patients, it is still an important difficulty in clinics. Patients often fail to mobilize adequately due to factors such as fear of falling, concerns about damaging the prosthesis, pain, lack of motivation, unawareness of the importance of mobilization, and the presence of drains or catheters. In this context, it is essential to strengthen patients` readiness for mobilization during the preoperative period and to gradually assist them in standing and encourage mobilization in the postoperative period. Mobilization protocols consist of a series of sequential and planned movements designed to improve the patient`s current level of mobility. These protocols help boost patients` self-confidence, thereby reducing the need for staff assistance in ambulation and transfer mechanics. In conclusion, mobilization plays a critical role in reducing postoperative complications, shortening hospital stays, and lowering mortality rates.