Neck pain is a common complaint in society and occur due to different causes. The majority may originate from the spine and soft tissues around to spine as well as from the non-spine tissues. The characteristics of the patient`s history and physical examination are valuable in terms of differential diagnosis. The first step in the differential diagnosis of a patient with neck pain is to exclude the possible underlying severe pathology. Second step is to differentiate the mechanical neck pain from radiculopathy or myelopathy.