Psychiatric assessment in chronic pain is important for differentiating non-medical courses in pain and to recognize psychiatric co-morbidities. In this review, comprehensive pain evaluation is explained, based on bio-psychosocial assessment. Vulnerability for chronic pain, distorted cognitions and behaviors are also discussed besides biological, psychological and social factors. Psychiatric assessment tools, functioning, coping and psychological factors in pain are reviewed. Psychiatric co-morbidities, such as depression, anxiety disorders, sleep disorders, psychological pain syndrome, somatic symptom disorder are explained. Also, tests that could be used for psychiatric evaluation are introduced briefly, and psychological etiology and co-morbid psychiatric disorders reviewed.