Anterior cervical discectomy and fusion (ACDF) is one of the most common procedures which is almost a `gold standard` in the treatment of symptomatic cervical degenerative disc disease. Good results following the anterior cervical spine surgery depends on good decompression, rapid and robust bone fusion, and nearly normal restoration of the biomechanical structure. ACDF surgery allows for direct decompression of the spinal cord and foramina; so when applied in the right patient and correctly, it is one of the procedures that offer the best results in spinal surgery. In this review, the discectomy and fusion procedure which is frequently applied in the surgical treatment of cervical radiculopathy will be explained.