TOTBİD Dergisi

TOTBİD Dergisi

2017, Cilt 16, Sayı, 3     (Sayfalar: 266-275)

Stem cell applications in musculoskeletal system diseases

Işık Akgün 1

1 Gayrettepe Florance Nightingale Hastanesi, İstanbul

DOI: 10.14292/totbid.dergisi.2017.36
Görüntüleme: 495
İndirme : 844

Recently, the adult stem cell treatment has gained a great interest for cartilage lesions. Indeed, regenerative medicine has a growing implication in almost every medical specialty. First clinical application in our country has been realized in 2009, and with the new technologies in this field, treatments have increased since then. There are mainly two methods for the preparation of these biological products for regenerative treatments: obtaining cultured products by amplification of cells in GMP laboratories, or preparing regenerative cell concentrates directly from bone morrow and fat tissues which lets us use the product in a single procedure. For the orthopedic procedures mainly the scaffolds embedded with stem cell are constructed in local cartilage lesions with open surgery techniques, whereas intraarticular regenerative cell cocktail injections are preferred for degenerated joint problems.

Anahtar Kelimeler : adult stem cell; stem cell; regenerative medicine; cartilage lesions