Ankle arthritis is characterized by pain especially aggravated by standing and/or walking, swelling, limping and loss of motion in the joint. Ankle arthritis most commonly results from trauma (either a severe injury or recurrent microtraumas). Also, deformities leading to malalignment; inflammatory arthritis (rheumatoid arthritis, systemic lupus erythematosus or gout) and septic arthritis of the joint may end with the defined pathology. Like other arthritic conditions it is associated with cartilage loss. In non-operative management, limiting the amount of loading to joint (weight loss, activity modification and using cane or crutches), nonsteroidal antiinflammatory drugs and braces may be considered. In this paper it mainly will be focused on ankle arthrodesis. Ankle arthroscopic debridement and arthroplasty are other surgical options. In this review we focused on the tibiotalar arthrodesis.