Platelet Rich Plasma (PRP) is defined as plasma containing a higher concentration of platelets from their normal upper limit. The main use of PRP is the release of alfa granule-rich content of platelets into the injection site. Alfa and dens granules in platelets and the contents of these granules are important in inflammation, angiogenesis, atherosclerosis and wound healing other than their known basic functions. In recent years there are many promising developments in treating musculoskeletal injuries and diseases with PRP practices. As the famous quote `What you`re searching for, search in yourself` says, it is predictable that as we learn more about our own organism there will come an era that new methods and technics are available.